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Proteins govern most biological processes and functions. Recently, much attention has been paid to study the entire protein sets available in a cell. The term "proteome", a portmanteau of protein and genome, was coined by Marc Wilkins in 1994 and broadly defined as the total set of proteins that could be expressed in a sample or organism at a given time or the set of proteins that can be detected by some method. This varies with time and distinct requirements, or stresses. The related term ''proteomics'' was originally coined by Marc Wilkins and colleagues and is now widely identified as one of the omics- the set of post-genomic technologies that seek to further understand the genome in the molecules it encodes, their functions, interactions, and connected properties.